Sleeping Sickness, also known as african trypanosomiasis, is related to parasitic ectoparasitic infectious disease and trypanosomiasis. An important gene associated with Sleeping Sickness is APOL1 (Apolipoprotein L1), and among its related pathways/superpathways are Metabolism and Regulation of expression of SLITs and ROBOs. The drugs Eflornithine and Nifurtimox have been mentioned in the context of this disorder. Affiliated tissues include brain and heart, and related phenotypes are abnormality of the nervous system and narcolepsy