Sialolithiasis, also known as stone of salivary gland or duct, is related to salivary gland disease and aplasia of lacrimal and salivary glands. An important gene associated with Sialolithiasis is STATH (Statherin), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Thyroxine (thyroid hormone) production. The drug Anesthetics has been mentioned in the context of this disorder. Affiliated tissues include salivary gland and tongue.