Sulfamethoxazole Allergy, also known as sulphamethoxazole allergy, is related to co-trimoxazole allergy and hypertrophy of tongue papillae. An important gene associated with Sulfamethoxazole Allergy is CYP2C8 (Cytochrome P450 Family 2 Subfamily C Member 8), and among its related pathways/superpathways are Imipramine/Desipramine Pathway, Pharmacokinetics and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. Affiliated tissues include t cells, and related phenotype is Synthetic lethal with MLN4924 (a NAE inhibitor).