Self-Improving Collodion Baby, also known as self-healing collodion baby, is related to ichthyosis, congenital, autosomal recessive 3 and ichthyosis, congenital, autosomal recessive 2. An important gene associated with Self-Improving Collodion Baby is ALOX12B (Arachidonate 12-Lipoxygenase, 12R Type), and among its related pathways/superpathways are Fatty acid metabolism and Prostaglandin 2 biosynthesis and metabolism FM. The drug Orange has been mentioned in the context of this disorder. Affiliated tissues include eye and skin, and related phenotypes are ichthyosis and limitation of joint mobility