Sjogren Syndrome

Alias:
Sjogren's Syndrome
Sicca Syndrome
Sjögren Syndrome
Keratoconjunctivitis Sicca
Sjögren's Syndrome
Keratoconjunctivitis Sicca-Xerostomia
Secreto-Inhibitor-Xerodermostenosis
Dacryosialoadenopathia Atrophicans
Gougerot-Houwer-Sjogren Syndrome
Gougerot-Sjogren Syndrome
Sjogren-Gougerot Syndrome
Dry Eye Syndromes
Sjogrens Syndrome
Xerodermosteosis
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Sjogren Syndrome, also known as sjogren's syndrome, is related to aplasia of lacrimal and salivary glands and salivary gland disease, and has symptoms including dryness of eye, eye manifestations and back pain. An important gene associated with Sjogren Syndrome is IFNG-AS1 (IFNG Antisense RNA 1), and among its related pathways/superpathways are NF-kappaB Signaling and Apoptosis and Autophagy. The drugs Oxybutynin and Mirabegron have been mentioned in the context of this disorder. Affiliated tissues include eye and salivary gland, and related phenotypes are autoimmunity and abnormality of metabolism/homeostasis
Related ID:
MESH:D012859
ICD11:1923044320

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AR
Unknown
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36
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20

Medical Symptom

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Gene & Mutation

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References Literature

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