Shwartzman Phenomenon, also known as shwartzman reaction, is related to toxic shock syndrome and purpura. An important gene associated with Shwartzman Phenomenon is ITGAM (Integrin Subunit Alpha M), and among its related pathways/superpathways are Innate Immune System and TGF-Beta Pathway. Affiliated tissues include skin and endothelial, and related phenotypes are homeostasis/metabolism and cellular