Sheehan Syndrome, also known as sheehan's syndrome, is related to premature ovarian failure 7 and pituitary tumors. An important gene associated with Sheehan Syndrome is PRL (Prolactin), and among its related pathways/superpathways are Peptide hormone metabolism and G alpha (s) signalling events. Affiliated tissues include pituitary and hypothalamus, and related phenotypes are chronic fatigue and panhypopituitarism