Second-Degree Atrioventricular Block, also known as incomplete atrioventricular block, second degree nos, is related to atrioventricular block and progressive familial heart block. An important gene associated with Second-Degree Atrioventricular Block is TRIM21 (Tripartite Motif Containing 21), and among its related pathways/superpathways are Cardiac conduction and Sudden infant death syndrome (SIDS) susceptibility pathways. Affiliated tissues include heart and atrioventricular node, and related phenotypes are Increased shRNA abundance (Z-score > 2) and nervous system