Sclerosteosis 1 (SOST1)

Sclerosteosis 1, also known as sost1, is related to van buchem disease and craniodiaphyseal dysplasia, and has symptoms including unspecified visual loss An important gene associated with Sclerosteosis 1 is SOST (Sclerostin), and among its related pathways/superpathways are Vitamin D receptor pathway and RUNX2 regulates bone development. The drug Diphosphonates has been mentioned in the context of this disorder. Affiliated tissues include bone and medulla oblongata, and related phenotypes are frontal bossing and large face