Sickle Cell-Beta-Thalassemia Disease Syndrome, also known as hbs-beta-thalassemia syndrome, is related to beta-thalassemia and thalassemia. An important gene associated with Sickle Cell-Beta-Thalassemia Disease Syndrome is HBB (Hemoglobin Subunit Beta). The drugs Hydroxyurea and Fludarabine have been mentioned in the context of this disorder. Affiliated tissues include brain and bone marrow.