Sickle Cell Disease (SKCA)

Alias:
Sickle Cell Anemia
Hemoglobin Sc Disease
Anemia, Sickle Cell
Hb Ss Disease
Hb-Ss Disease Without Crisis
Sickle Cell Trait
Hereditary Haemoglobinopathy Disorder Homozygous for Haemoglobin S
Hb-S - [sickle Cell Haemoglobin] Carrier
Sickle-Cell/hb-C Disease Without Crisis
Hbas - [sickle Cell Haemoglobin Trait]
Haemoglobin Sickle Cell Trait Disorder
Sickling Disorder Due to Haemoglobin S
Hb-Ss Disease with Vaso-Occlusive Pain
Sickling Disorder Due to Hemoglobin S
Sickle-Cell Trait Haemoglobin Disease
Hemoglobin S Disease Without Crisis
Hbas - [heterozygous Haemoglobin S]
Hb S Disease with Mention of Crisis
Sickle-Cell Anaemia Without Crisis
Haemoglobin Ss Disease with Crisis
Sickle-Cell Heterozygous Disorder
Sickle-Cell Disorder with Crisis
Sickle-Cell Haemoglobin Disease
Sickle-Cell Anaemia with Crisis
Heterozygous Sickle Cell Trait
Sickle Cell Haemoglobin Trait
Sickle-Cell Disease Carrier
Scd - [sickle Cell Disease]
Sca - [sickle Cell Anaemia]
Hb-Ss Disease with Crisis
Haemoglobin a-S Genotype
As - [sickle Cell Trait]
Sickle-Cell Disorder Nos
Sickle Cell Disease Nos
Sickle-Cell Anaemia Nos
Haemoglobin Sc Disease
Haemoglobin Ss Disease
Sickle Cell Disorders
Haemoglobin S Disease
Vaso-Occlusive Crisis
Hemoglobin S Disease
Sickle Cell Disorder
Sickle Cell Syndrome
Sickle Cell Anaemia
Hbss Without Crisis
Sickle Cell Crisis
Hb-S/hb-C Disease
Hbss with Crisis
Herrick Anaemia
Drepanocytosis
Hb Sc Disease
Hb S Disease
Hbs Disease
Skca
Scd
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Sickle Cell Disease, also known as sickle cell anemia, is related to hereditary persistence of fetal hemoglobin-sickle cell disease syndrome and acute chest syndrome, and has symptoms including abdominal pain, angina pectoris and chest pain. An important gene associated with Sickle Cell Disease is HBB (Hemoglobin Subunit Beta), and among its related pathways/superpathways are Glucose / Energy Metabolism and Binding and Uptake of Ligands by Scavenger Receptors. The drugs Sulfadoxine and Pyrimethamine have been mentioned in the context of this disorder. Affiliated tissues include Blood, bone marrow and bone, and related phenotypes are chronic hemolytic anemia and hemolytic anemia
Related ID:
MESH:D000755
ICD11:1711513381

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AR
All ages
1-5/10000
75
736
280

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

#
Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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