Schnitzler Syndrome

Schnitzler Syndrome, also known as chronic urticaria with macroglobulinemia, is related to urticaria and cryopyrin-associated periodic syndrome, and has symptoms including rash An important gene associated with Schnitzler Syndrome is IL1R1 (Interleukin 1 Receptor Type 1), and among its related pathways/superpathways are Infectious disease and Innate Immune System. The drugs Rilonacept and Dapansutrile have been mentioned in the context of this disorder. Affiliated tissues include bone and spleen, and related phenotypes are splenomegaly and hepatomegaly