Reye Syndrome, also known as reye's syndrome, is related to long-chain 3-hydroxyacyl-coa dehydrogenase deficiency and acyl-coa dehydrogenase, short-chain, deficiency of, and has symptoms including back pain, headache and pain. An important gene associated with Reye Syndrome is ACADM (Acyl-CoA Dehydrogenase Medium Chain), and among its related pathways/superpathways are Metabolism and Fatty acid metabolism. Affiliated tissues include liver and brain, and related phenotypes are liver/biliary system and homeostasis/metabolism