Reynolds Syndrome (REYNS)

Reynolds Syndrome, also known as primary biliary cirrhosis and systemic scleroderma, is related to scleroderma, familial progressive and primary biliary cholangitis, and has symptoms including icterus and pruritus. An important gene associated with Reynolds Syndrome is LBR (Lamin B Receptor), and among its related pathways/superpathways are Cell Cycle, Mitotic and Separation of Sister Chromatids. Affiliated tissues include liver and skin, and related phenotypes are hepatomegaly and generalized abnormality of skin