Retinal Dystrophy, Iris Coloboma, and Comedogenic Acne Syndrome, is also known as progressive retinal dystrophy due to retinol transport defect, and has symptoms including exanthema and pruritus. An important gene associated with Retinal Dystrophy, Iris Coloboma, and Comedogenic Acne Syndrome is RBP4 (Retinol Binding Protein 4). The drugs Calcipotriol and Sarecycline have been mentioned in the context of this disorder. Affiliated tissues include eye and skin, and related phenotypes are microcornea and iris coloboma