Retinitis Pigmentosa 46, also known as rp46, is related to chromium allergic contact dermatitis and type 1 diabetes mellitus 8. An important gene associated with Retinitis Pigmentosa 46 is IDH3B (Isocitrate Dehydrogenase (NAD(+)) 3 Non-Catalytic Subunit Beta), and among its related pathways/superpathways are T-cell activation SARS-CoV-2 and Allograft rejection. Affiliated tissues include retina and eye, and related phenotypes are visual impairment and rod-cone dystrophy