Retinoblastoma (RB1)

Retinoblastoma(来自ICD-11)
别称:
Trilateral Retinoblastoma
Rb
Childhood Cancer Retinoblastoma
Non-Hereditary Retinoblastoma
Malignant Neoplasm of Retina
Retinoblastoma, Trilateral
Neuroblastoma of Retina
Rb - Retinoblastoma
Retinal Neoplasms
Glioma, Retinal
Rb1
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Retinoblastoma, also known as trilateral retinoblastoma, is related to familial retinoblastoma and bilateral retinoblastoma. An important gene associated with Retinoblastoma is RB1 (RB Transcriptional Corepressor 1), and among its related pathways/superpathways are Chks in Checkpoint Regulation and DNA Damage. The drugs Sargramostim and Nicotine have been mentioned in the context of this disorder. Affiliated tissues include retina and eye, and related phenotypes are retinoblastoma and strabismus
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相关ID:
MESH:D012175
ICD11:1855353671

基础信息

遗传方式
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参考文献
MALACARDS
AD
Newborn
<1/1000000
112
1285
323

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靶点药物

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MGI
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