Reticulate Acropigmentation of Kitamura (RAK)

Reticulate Acropigmentation of Kitamura, also known as rak, is related to dowling-degos disease and dowling-degos disease 1. An important gene associated with Reticulate Acropigmentation of Kitamura is ADAM10 (ADAM Metallopeptidase Domain 10), and among its related pathways/superpathways are Pre-NOTCH Expression and Processing and ATP/ITP metabolism. Affiliated tissues include skin, and related phenotypes are hyperkeratosis and macule