Reticulosarcoma, also known as diffuse large b-cell lymphoma, is related to langerhans cell histiocytosis and lymphosarcoma. An important gene associated with Reticulosarcoma is TNFRSF8 (TNF Receptor Superfamily Member 8), and among its related pathways/superpathways are Innate Immune System and Signal Transduction. The drugs Lomustine and Idarubicin have been mentioned in the context of this disorder. Affiliated tissues include t cells and nk cells, and related phenotypes are growth/size/body region and immune system