Resistance to Thyroid Hormone Due to a Mutation in Thyroid Hormone Receptor Alpha, also known as resistance to thyroid hormone due to a mutation in tra, is related to hypothyroidism and osteochondrodysplasia. An important gene associated with Resistance to Thyroid Hormone Due to a Mutation in Thyroid Hormone Receptor Alpha is THRA (Thyroid Hormone Receptor Alpha). The drugs Tranexamic acid and Coagulants have been mentioned in the context of this disorder. Affiliated tissues include thyroid and tongue.