Ring Dermoid of Cornea, also known as ring dermoid syndrome, is related to osteoarthritis and melancholic depression. An important gene associated with Ring Dermoid of Cornea is PITX2 (Paired Like Homeodomain 2), and among its related pathways/superpathways are Cytosolic sulfonation of small molecules and Heart development. Affiliated tissues include eye and skin, and related phenotypes are amblyopia and abnormal cornea morphology