Rem Sleep Behavior Disorder, also known as rapid eye movement sleep behavior disorder, is related to machado-joseph disease and tremor. An important gene associated with Rem Sleep Behavior Disorder is SNCA (Synuclein Alpha), and among its related pathways/superpathways are Neuroscience and Circadian Clock. The drugs Sodium oxybate and Iodine have been mentioned in the context of this disorder. Affiliated tissues include eye and brain, and related phenotypes are nervous system and growth/size/body region