Rh Isoimmunization, also known as rh incompatibility affecting management of mother, is related to neonatal anemia and deficiency anemia. An important gene associated with Rh Isoimmunization is EPO (Erythropoietin), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Cell surface interactions at the vascular wall. Affiliated tissues include placenta and fetal lung, and related phenotypes are muscle and cardiovascular system