Rheumatoid Factor-Negative Polyarticular Juvenile Idiopathic Arthritis, also known as juvenile rheumatoid factor-negative polyarthritis, is related to juvenile rheumatoid arthritis and polyarticular juvenile idiopathic arthritis. An important gene associated with Rheumatoid Factor-Negative Polyarticular Juvenile Idiopathic Arthritis is ANKRD55 (Ankyrin Repeat Domain 55), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Abatacept and Adalimumab have been mentioned in the context of this disorder. Affiliated tissues include eye and bone, and related phenotypes are arthritis and joint stiffness