Rheumatic Fever, also known as acute rheumatic fever, is related to rheumatic myocarditis and wissler-fanconi syndrome, and has symptoms including carditis, polyarthritis and chorea. An important gene associated with Rheumatic Fever is MYOM2 (Myomesin 2), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Tofacitinib and Etanercept have been mentioned in the context of this disorder. Affiliated tissues include heart and skin, and related phenotypes are nausea and vomiting and arthritis