Rhabdomyosarcoma 2 (RMS2)

Rhabdomyosarcoma 2, also known as alveolar rhabdomyosarcoma, is related to embryonal rhabdomyosarcoma and sarcoma. An important gene associated with Rhabdomyosarcoma 2 is PAX3 (Paired Box 3), and among its related pathways/superpathways are ERK Signaling and Prolactin Signaling. The drugs Lenograstim and Sargramostim have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle and bone marrow, and related phenotypes are alveolar rhabdomyosarcoma and Synthetic lethal with MLN4924 (a NAE inhibitor)