Refractory Anemia

Refractory Anemia, also known as rars-t [refractory anaemia with ringed sideroblasts associated with marked thrombocytosis], is related to acquired idiopathic sideroblastic anemia and refractory anemia with excess blasts. An important gene associated with Refractory Anemia is TET2 (Tet Methylcytosine Dioxygenase 2), and among its related pathways/superpathways is Hematopoietic Stem Cells and Lineage-specific Markers. The drugs Dopamine and Magnesium citrate have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and bone, and related phenotypes are myelodysplasia and anemia of inadequate production