Refractory Cytopenia with Multilineage Dysplasia is related to refractory anemia and myelodysplastic syndrome. An important gene associated with Refractory Cytopenia with Multilineage Dysplasia is SF3B1 (Splicing Factor 3b Subunit 1). The drugs Vorinostat and Methotrexate have been mentioned in the context of this disorder. Affiliated tissues include myeloid and bone marrow, and related phenotypes are HIV Rev nuclear localization and mortality/aging