Refractory Hairy Cell Leukemia is related to hairy cell leukemia and capillary leak syndrome. An important gene associated with Refractory Hairy Cell Leukemia is CD22 (CD22 Molecule), and among its related pathways/superpathways are Signaling by NTRKs and Immune response Fc epsilon RI pathway. The drugs Immunoconjugates and Protective Agents have been mentioned in the context of this disorder. Affiliated tissues include t cells and liver.