Rectal Disease, also known as rectal disorders, is related to proctitis and anus disease, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Rectal Disease is CD4 (CD4 Molecule), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Pleural mesothelioma. The drugs Benzocaine and Bupivacaine have been mentioned in the context of this disorder. Affiliated tissues include colon and lymph node, and related phenotypes are homeostasis/metabolism and growth/size/body region