Rubeosis Iridis is related to retinal ischemia and central retinal vein occlusion. An important gene associated with Rubeosis Iridis is PRR4 (Proline Rich 4), and among its related pathways/superpathways are Apoptotic Pathways in Synovial Fibroblasts and Phospholipase-C Pathway. The drugs Bevacizumab and Antineoplastic Agents, Immunological have been mentioned in the context of this disorder. Affiliated tissues include eye and retina.