Quadriplegia, also known as tetraplegia, is related to leukodystrophy, hypomyelinating, 6 and spastic quadriplegic cerebral palsy, and has symptoms including hemiplegia, ophthalmoplegia and muscle weakness. An important gene associated with Quadriplegia is ELOVL4 (ELOVL Fatty Acid Elongase 4), and among its related pathways/superpathways are Oligodendrocyte specification and differentiation, leading to myelin components for CNS and Mitochondrial complex II assembly. The drugs Midodrine and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and brain, and related phenotypes are homeostasis/metabolism and nervous system