Pyelonephritis is related to chronic pyelonephritis and acute pyelonephritis. An important gene associated with Pyelonephritis is TLR4 (Toll Like Receptor 4), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Tigecycline and Colistin have been mentioned in the context of this disorder. Affiliated tissues include kidney and liver, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and homeostasis/metabolism