Pyoderma Gangrenosum

Pyoderma Gangrenosum, also known as phagedenic pyoderma, is related to pyogenic sterile arthritis, pyoderma gangrenosum, and acne and crohn's disease. An important gene associated with Pyoderma Gangrenosum is PSTPIP1 (Proline-Serine-Threonine Phosphatase Interacting Protein 1), and among its related pathways/superpathways are MIF Mediated Glucocorticoid Regulation and Innate Immune System. The drugs Endothelial Growth Factors and Adalimumab have been mentioned in the context of this disorder. Affiliated tissues include skin and bone, and related phenotypes are fever and skin ulcer