Pituitary Hormone Deficiency, Combined, 6, also known as cphd6, is related to pituitary hormone deficiency, combined 1. An important gene associated with Pituitary Hormone Deficiency, Combined, 6 is OTX2 (Orthodenticle Homeobox 2). Affiliated tissues include pituitary and thyroid, and related phenotypes are short stature and neonatal hypoglycemia