Pituitary Apoplexy, also known as pituitary tumor apoplexy, is related to nelson syndrome and premature ovarian failure 7. An important gene associated with Pituitary Apoplexy is PRL (Prolactin), and among its related pathways/superpathways are TGF-Beta Pathway and Signal Transduction. Affiliated tissues include pituitary and caudate nucleus, and related phenotypes are bitemporal hemianopia and thunderclap headache