Patent Foramen Ovale

Patent Foramen Ovale, also known as atrial septal defect, ostium secundum type, is related to tricuspid atresia and hypoplastic right heart syndrome. An important gene associated with Patent Foramen Ovale is TBX5 (T-Box Transcription Factor 5), and among its related pathways/superpathways are Cardiac conduction and MAPK signaling pathway. The drugs Warfarin and Rivaroxaban have been mentioned in the context of this disorder. Affiliated tissues include heart and brain, and related phenotypes are left-to-right shunt and fatigue