Post-Thrombotic Syndrome, also known as postphlebitic syndrome, is related to chronic venous insufficiency and vitamin k deficiency bleeding. An important gene associated with Post-Thrombotic Syndrome is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Rivaroxaban and Reviparin have been mentioned in the context of this disorder. Affiliated tissues include skin and endothelial, and related phenotypes are homeostasis/metabolism and nervous system