Postpoliomyelitis Syndrome

Alias:
Postpolio Syndrome
Postpoliomyelitic Syndrome
Postpoliomyelitis Sequelae
Post-Polio Syndrome
Postpolio Sequelae
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Postpoliomyelitis Syndrome, also known as postpolio syndrome, is related to progressive muscular atrophy and lateral sclerosis. An important gene associated with Postpoliomyelitis Syndrome is MTNAP1 (Mitochondrial Nucleoid Associated Protein 1), and among its related pathways/superpathways are Oligodendrocyte specification and differentiation, leading to myelin components for CNS and Interactions of natural killer cells in pancreatic cancer. The drugs Modafinil and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and skeletal muscle, and related phenotypes are muscle weakness and pain
Related ID:
MESH:D016262

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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Adolescent
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14
164
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Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Related Drugs

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Phase
No data available

Disease Model

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MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
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IF
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