Psoriasis 2 (PSORS2)

Psoriasis 2, also known as psoriasis vulgaris, is related to psoriasis 6 and pustulosis of palm and sole, and has symptoms including exanthema, pruritus and psoriasiform rash. An important gene associated with Psoriasis 2 is CARD14 (Caspase Recruitment Domain Family Member 14). The drugs Vedolizumab and Dapsone have been mentioned in the context of this disorder. Affiliated tissues include skin and t cells, and related phenotypes are hyperkeratosis and psoriasiform dermatitis