Psoriatic Arthritis (PSORAS)

Psoriatic Arthritis, also known as psoriatic arthropathy, is related to spondyloarthropathy 1 and juvenile rheumatoid arthritis, and has symptoms including back pain, muscle cramp and sciatica. An important gene associated with Psoriatic Arthritis is LTA (Lymphotoxin Alpha), and among its related pathways/superpathways are Innate Immune System and PAK Pathway. The drugs Abatacept and Certolizumab pegol have been mentioned in the context of this disorder. Affiliated tissues include skin and bone, and related phenotypes are Increased shRNA abundance (Z-score > 2) and homeostasis/metabolism