Pseudohypoaldosteronism, Type I, Autosomal Dominant (PHA1A)

Pseudohypoaldosteronism, Type I, Autosomal Dominant, also known as autosomal dominant pseudohypoaldosteronism type 1, is related to pseudohypoaldosteronism type 1 and urinary tract infection, and has symptoms including diarrhea and vomiting. An important gene associated with Pseudohypoaldosteronism, Type I, Autosomal Dominant is NR3C2 (Nuclear Receptor Subfamily 3 Group C Member 2), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Neuropathic Pain-Signaling in Dorsal Horn Neurons. The drugs Cefepime and Cefepime-zidebactam have been mentioned in the context of this disorder. Affiliated tissues include kidney, and related phenotypes are hyperkalemia and hyponatremia