Pseudoxanthoma Elasticum (PXE)

Pseudoxanthoma Elasticum, also known as pxe, is related to arterial calcification of infancy and angioid streaks, and has symptoms including angina pectoris An important gene associated with Pseudoxanthoma Elasticum is ABCC6 (ATP Binding Cassette Subfamily C Member 6), and among its related pathways/superpathways are Glucose / Energy Metabolism and Endochondral ossification with skeletal dysplasias. The drugs Dexlansoprazole and Lansoprazole have been mentioned in the context of this disorder. Affiliated tissues include skin and eye, and related phenotypes are retinopathy and thickened nuchal skin fold