Pseudobulbar Palsy

Pseudobulbar Palsy, also known as pseudobulbar paralysis, is related to cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1 and cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2, and has symptoms including dysarthria, dysphagia and spasticity. An important gene associated with Pseudobulbar Palsy is NOTCH3 (Notch Receptor 3), and among its related pathways/superpathways are Neuroscience and Copper homeostasis. Affiliated tissues include tongue and brain, and related phenotypes are Increased shRNA abundance (Z-score > 2) and homeostasis/metabolism