Protoporphyria, Erythropoietic, 1 (EPP1)

Protoporphyria, Erythropoietic, 1, also known as erythropoietic protoporphyria, is related to x-linked protoporphyria and cutaneous porphyria, and has symptoms including edema, pruritus and burning sensation. An important gene associated with Protoporphyria, Erythropoietic, 1 is FECH (Ferrochelatase), and among its related pathways/superpathways are Metabolism and Insulin receptor recycling. The drugs Afamelanotide and Colestipol have been mentioned in the context of this disorder. Affiliated tissues include liver and skin, and related phenotypes are erythema and cutaneous photosensitivity