Preterm Premature Rupture of the Membranes, also known as preterm premature rupture of membranes, is related to endometritis and chorioamnionitis. An important gene associated with Preterm Premature Rupture of the Membranes is SERPINH1 (Serpin Family H Member 1), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Roxithromycin and Cefuroxime have been mentioned in the context of this disorder. Affiliated tissues include thymus and t cells, and related phenotypes are premature rupture of membranes and homeostasis/metabolism