Pure Autonomic Failure (PAF)

Alias:
Idiopathic Orthostatic Hypotension
Bradbury-Eggleston Syndrome
Pure Idiopatic Dysautonomia
Pure Dysautonomia
Paf
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Pure Autonomic Failure, also known as idiopathic orthostatic hypotension, is related to multiple system atrophy 1 and dysautonomia. An important gene associated with Pure Autonomic Failure is DBH (Dopamine Beta-Hydroxylase), and among its related pathways/superpathways is Neuroscience. The drugs Naloxone and Diazoxide have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and brain, and related phenotypes are abnormal autonomic nervous system physiology and orthostatic hypotension
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Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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Adult
1-9/1000000
3
49
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Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Score
Mutations
No data available

Related Drugs

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CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
Journal
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IF
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