Pertussis

Alias:
Whooping Cough
Bordetella Infections
Bordetella Infection
Whooping Cough Due to Unspecified Organism
Infection Due to Bordetella Parapertussis
Whooping Cough Due to B. Parapertussis
Whooping Cough, Unspecified Organism
Bordetella Pertussis Infection
Wc - [whooping Cough]
Wc - Whooping Cough
Tussis Convulsiva
Bordetellosis
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Pertussis, also known as whooping cough, is related to tetanus and cholera, and has symptoms including coughing, fever and pruritus. An important gene associated with Pertussis is TLR4 (Toll Like Receptor 4), and among its related pathways/superpathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. The drugs BCG vaccine and Montelukast have been mentioned in the context of this disorder. Affiliated tissues include smooth muscle and dorsal root ganglion, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Reduced mammosphere formation
Related ID:
MESH:D001885
ICD11:1287021540

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
All ages
1-9/1000000
27
256
3

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

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CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
Journal
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IF
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