Pearson Marrow-Pancreas Syndrome

Pearson Marrow-Pancreas Syndrome, also known as pearson syndrome, is related to sideroblastic anemia and 3-methylglutaconic aciduria. An important gene associated with Pearson Marrow-Pancreas Syndrome is MT-CO2 (Mitochondrially Encoded Cytochrome C Oxidase II), and among its related pathways/superpathways are Metabolism and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. The drugs DL-alpha-Tocopherol and Tocopherol have been mentioned in the context of this disorder. Affiliated tissues include Pancreas and bone marrow, and related phenotypes are neutropenia and reticulocytosis