Persistent Polyclonal B-Cell Lymphocytosis (PPBL)

Persistent Polyclonal B-Cell Lymphocytosis(来自ICD-11)

别称:

Ppbl

Persistent Polyclonal B-Cell Lymphocytosis with Binucleated Lymphocytes

Lymphocytosis, B-Cell, Polyclonal, Persistent

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Persistent Polyclonal B-Cell Lymphocytosis, also known as ppbl, is related to b-cell expansion with nfkb and t-cell anergy and lymphoproliferative syndrome. An important gene associated with Persistent Polyclonal B-Cell Lymphocytosis is CARD11 (Caspase Recruitment Domain Family Member 11). Affiliated tissues include b cells and bone marrow, and related phenotypes are splenomegaly and hepatomegaly

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